Activation of nuclear factor-kappa B by TNF promotes nucleus pulposus mineralization through inhibition of ANKH and ENPP1

Spontaneous mineralization of the nucleus pulposus (NP) has been observed in cases of intervertebral disc degeneration (IDD). Inflammatory cytokines have been implicated in mineralization of multiple tissues through their modulation of expression of factors that enable or inhibit mineralization, inc...

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Detalles Bibliográficos
Autores principales: Krzyzanowska, Agata K., Frawley, Robert J., Damle, Sheela, Chen, Tony, Otero, Miguel, Cunningham, Matthew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050288/
https://www.ncbi.nlm.nih.gov/pubmed/33859255
http://dx.doi.org/10.1038/s41598-021-87665-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050288/
https://www.ncbi.nlm.nih.gov/pubmed/33859255
http://dx.doi.org/10.1038/s41598-021-87665-2

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