FCN3 functions as a tumor suppressor of lung adenocarcinoma through induction of endoplasmic reticulum stress

In this study, we report a novel function of FCN3 (Ficolin 3), a secreted lectin capable of activating the complement pathway, as a tumor suppressor of lung adenocarcinoma (LUAD). First, the expression of FCN3 was strongly down-regulated in cancer tissues compared to matched normal lung tissues, and...

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Detalles Bibliográficos
Autores principales: Jang, Haeyeon, Jun, Yukyung, Kim, Suyeon, Kim, Eunjeong, Jung, Yeonjoo, Park, Byung Jo, Lee, Jinseon, Kim, Jhingook, Lee, Sanghyuk, Kim, Jaesang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050313/
https://www.ncbi.nlm.nih.gov/pubmed/33859174
http://dx.doi.org/10.1038/s41419-021-03675-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050313/
https://www.ncbi.nlm.nih.gov/pubmed/33859174
http://dx.doi.org/10.1038/s41419-021-03675-y

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