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Microglial neuropilin-1 promotes oligodendrocyte expansion during development and remyelination by trans-activating platelet-derived growth factor receptor

Nerve-glia (NG2) glia or oligodendrocyte precursor cells (OPCs) are distributed throughout the gray and white matter and generate myelinating cells. OPCs in white matter proliferate more than those in gray matter in response to platelet-derived growth factor AA (PDGF AA), despite similar levels of i...

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Detalles Bibliográficos
Autores principales: Sherafat, Amin, Pfeiffer, Friederike, Reiss, Alexander M., Wood, William M., Nishiyama, Akiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050320/
https://www.ncbi.nlm.nih.gov/pubmed/33859199
http://dx.doi.org/10.1038/s41467-021-22532-2