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Microglial neuropilin-1 promotes oligodendrocyte expansion during development and remyelination by trans-activating platelet-derived growth factor receptor
Nerve-glia (NG2) glia or oligodendrocyte precursor cells (OPCs) are distributed throughout the gray and white matter and generate myelinating cells. OPCs in white matter proliferate more than those in gray matter in response to platelet-derived growth factor AA (PDGF AA), despite similar levels of i...
Autores principales: | Sherafat, Amin, Pfeiffer, Friederike, Reiss, Alexander M., Wood, William M., Nishiyama, Akiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050320/ https://www.ncbi.nlm.nih.gov/pubmed/33859199 http://dx.doi.org/10.1038/s41467-021-22532-2 |
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