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Posttranslational and Therapeutic Control of Gasdermin-Mediated Pyroptosis and Inflammation
Pyroptosis is a proinflammatory form of cell death, mediated by membrane pore-forming proteins called gasdermins. Gasdermin pores allow the release of the pro-inflammatory cytokines IL-1β and IL-18 and cause cell swelling and cell lysis leading to release of other intracellular proteins that act as...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050342/ https://www.ncbi.nlm.nih.gov/pubmed/33868312 http://dx.doi.org/10.3389/fimmu.2021.661162 |