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Citrus-derived DHCP inhibits mitochondrial complex II to enhance TRAIL sensitivity via ROS-induced DR5 upregulation

Heat-modified citrus pectin, a water-soluble indigestible polysaccharide fiber derived from citrus fruits and modified by temperature treatment, has been reported to exhibit anticancer effects. However, the bioactive fractions and their mechanisms remain unclear. In this current study, we isolated a...

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Detalles Bibliográficos
Autores principales: Chen, Lei, Hao, Miao, Yan, Jingmin, Sun, Lin, Tai, Guihua, Cheng, Hairong, Zhou, Yifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050394/
https://www.ncbi.nlm.nih.gov/pubmed/33676890
http://dx.doi.org/10.1016/j.jbc.2021.100515