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The Use of Bruton’s Tyrosine Kinase Inhibitors to Treat Allergic Disorders

PURPOSE OF REVIEW: Studies show that inhibitors of Bruton’s tyrosine kinase (BTKis), currently FDA-approved for the treatment of B cell malignancies, can prevent IgE-mediated reactions through broad inhibition of the FcεRI signaling pathway in human mast cells and basophils. This review will summari...

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Detalles Bibliográficos
Autor principal: Dispenza, Melanie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050815/
https://www.ncbi.nlm.nih.gov/pubmed/33880321
http://dx.doi.org/10.1007/s40521-021-00286-y