Trichostatin A downregulates bromodomain and extra-terminal proteins to suppress osimertinib resistant non-small cell lung carcinoma

BACKGROUND: The third-generation epithelial growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) have shown significant therapeutic effects on patients with non-small cell lung carcinoma (NSCLC) who carry active EGFR mutations, as well as those who have developed acquired resistance to the...

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Detalles Bibliográficos
Autores principales: Meng, Yuting, Qian, Xixi, Zhao, Li, Li, Nan, Wu, Shengjie, Chen, Baoan, Sun, Tong, Wang, Xuerong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050891/
https://www.ncbi.nlm.nih.gov/pubmed/33858423
http://dx.doi.org/10.1186/s12935-021-01914-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050891/
https://www.ncbi.nlm.nih.gov/pubmed/33858423
http://dx.doi.org/10.1186/s12935-021-01914-y

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