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IκBα targeting promotes oxidative stress-dependent cell death

BACKGROUND: Oxidative stress is a hallmark of many cancers. The increment in reactive oxygen species (ROS), resulting from an increased mitochondrial respiration, is the major cause of oxidative stress. Cell fate is known to be intricately linked to the amount of ROS produced. The direct generation...

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Detalles Bibliográficos
Autores principales: Carrà, Giovanna, Ermondi, Giuseppe, Riganti, Chiara, Righi, Luisella, Caron, Giulia, Menga, Alessio, Capelletto, Enrica, Maffeo, Beatrice, Lingua, Marcello Francesco, Fusella, Federica, Volante, Marco, Taulli, Riccardo, Guerrasio, Angelo, Novello, Silvia, Brancaccio, Mara, Piazza, Rocco, Morotti, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050912/
https://www.ncbi.nlm.nih.gov/pubmed/33863364
http://dx.doi.org/10.1186/s13046-021-01921-x