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Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), represents a global crisis. Key to SARS-CoV-2 therapeutic development is unraveling the mechanisms that drive high infectivity, broad tissue tropism, and severe pathology. Our 2.85-angstrom c...

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Detalles Bibliográficos
Autores principales: Toelzer, Christine, Gupta, Kapil, Yadav, Sathish K. N., Borucu, Ufuk, Davidson, Andrew D., Kavanagh Williamson, Maia, Shoemark, Deborah K., Garzoni, Frederic, Staufer, Oskar, Milligan, Rachel, Capin, Julien, Mulholland, Adrian J., Spatz, Joachim, Fitzgerald, Daniel, Berger, Imre, Schaffitzel, Christiane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050947/
https://www.ncbi.nlm.nih.gov/pubmed/32958580
http://dx.doi.org/10.1126/science.abd3255