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Modeling SARS-CoV-2 infection and its individual differences with ACE2-expressing human iPS cells

Genetic differences are a primary reason for differences in the susceptibility and severity of COVID-19. As induced pluripotent stem (iPS) cells maintain the genetic information of the donor, they can be used to model individual differences in SARS-CoV-2 infection in vitro. We found that human iPS c...

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Detalles Bibliográficos
Autores principales: Sano, Emi, Deguchi, Sayaka, Sakamoto, Ayaka, Mimura, Natsumi, Hirabayashi, Ai, Muramoto, Yukiko, Noda, Takeshi, Yamamoto, Takuya, Takayama, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051014/
https://www.ncbi.nlm.nih.gov/pubmed/33880436
http://dx.doi.org/10.1016/j.isci.2021.102428