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MicroRNA-665 facilitates cell proliferation and represses apoptosis through modulating Wnt5a/β-Catenin and Caspase-3 signaling pathways by targeting TRIM8 in LUSC

BACKGROUND: MicroRNAs (miRNAs) are involved in the oncogenesis, development and transformation of lung squamous cell carcinoma (LUSC). miR-665 is clinically significant and acts as a pivotal function in some cancers. Nevertheless, the effects and the potential mechanisms of miR-665 in human LUSC are...

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Detalles Bibliográficos
Autores principales: Chen, Tian-Jun, Zheng, Qi, Gao, Fei, Yang, Tian, Ren, Hui, Li, Yang, Chen, Ming-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051054/
https://www.ncbi.nlm.nih.gov/pubmed/33858426
http://dx.doi.org/10.1186/s12935-021-01913-z