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The SRSF1/circATP5B/miR-185-5p/HOXB5 feedback loop regulates the proliferation of glioma stem cells via the IL6-mediated JAK2/STAT3 signaling pathway

BACKGROUND: Glioma is the most common and malignant tumor of central nervous system. The tumor initiation, self-renewal, and multi-lineage differentiation abilities of glioma stem cells (GSCs) are responsible for glioma proliferation and recurrence. Although circular RNAs (circRNAs) play vital roles...

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Detalles Bibliográficos
Autores principales: Zhao, Junshuang, Jiang, Yang, Zhang, Haiying, Zhou, Jinpeng, Chen, Lian, Li, Hao, Xu, Jinkun, Zhang, Guoqing, Jing, Zhitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051130/
https://www.ncbi.nlm.nih.gov/pubmed/33858489
http://dx.doi.org/10.1186/s13046-021-01931-9