U2AF2 binds IL7R exon 6 ectopically and represses its inclusion

Interleukin 7 receptor α-chain is crucial for the development and maintenance of T cells and genetically associated with autoimmune disorders including multiple sclerosis (MS). Exon 6 of IL7R encodes for its transmembrane domain and regulated by alternative splicing (AS): Inclusion or skipping of IL...

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Detalles Bibliográficos
Autores principales: Schott, Geraldine, Galarza-Muñoz, Gaddiel, Trevino, Noe, Chen, Xiaoting, Weirauch, Matthew T., Gregory, Simon G., Bradrick, Shelton S., Garcia-Blanco, Mariano A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051268/
https://www.ncbi.nlm.nih.gov/pubmed/33568552
http://dx.doi.org/10.1261/rna.078279.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051268/
https://www.ncbi.nlm.nih.gov/pubmed/33568552
http://dx.doi.org/10.1261/rna.078279.120

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