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Saccharomyces cerevisiae Ecm2 modulates the catalytic steps of pre-mRNA splicing

Genetic, biochemical, and structural studies have elucidated the molecular basis for spliceosome catalysis. Splicing is RNA catalyzed and the essential snRNA and protein factors are well-conserved. However, little is known about how nonessential components of the spliceosome contribute to the reacti...

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Detalles Bibliográficos
Autores principales: van der Feltz, Clarisse, Nikolai, Brandon, Schneider, Charles, Paulson, Joshua C., Fu, Xingyang, Hoskins, Aaron A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051269/
https://www.ncbi.nlm.nih.gov/pubmed/33547186
http://dx.doi.org/10.1261/rna.077727.120