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RNA Peach and Mango: orthogonal two-color fluorogenic aptamers distinguish nearly identical ligands

Two-channel fluorogenic RNA aptamer-based imaging is currently challenging. While we have previously characterized the Mango series of aptamers that bind tightly and specifically to the green fluorophore TO1-Biotin, the next aim was to identify an effective fluorogenic aptamer partner for two-color...

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Detalles Bibliográficos
Autores principales: Kong, Kristen Y.S., Jeng, Sunny C.Y., Rayyan, Batool, Unrau, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051271/
https://www.ncbi.nlm.nih.gov/pubmed/33674421
http://dx.doi.org/10.1261/rna.078493.120