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A retrievable implant for the long-term encapsulation and survival of therapeutic xenogeneic cells

The long-term function of transplanted therapeutic cells typically requires systemic immune suppression. Here, we show that a retrievable implant comprising of a silicone reservoir and a porous polymeric membrane protects human cells encapsulated in it after implant transplantation in the intraperit...

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Detalles Bibliográficos
Autores principales: Bose, Suman, Volpatti, Lisa R., Thiono, Devina, Yesilyurt, Volkan, McGladian, Collin, Tang, Yaoyu, Facklam, Amanda, Wang, Amy, Jhunjhunwala, Siddharth, Veiseh, Omid, Hollister-Lock, Jennifer, Bhattacharya, Chandrabali, Weir, Gordon C., Greiner, Dale L., Langer, Robert, Anderson, Daniel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051527/
https://www.ncbi.nlm.nih.gov/pubmed/32231313
http://dx.doi.org/10.1038/s41551-020-0538-5