Novel chimeric TLR2/NOD2 agonist CL429 exhibited significant radioprotective effects in mice

Severe ionizing radiation causes the acute lethal damage of haematopoietic system and gastrointestinal tract. Here, we found CL429, the novel chimeric TLR2/NOD2 agonist, exhibited significant radioprotective effects in mice. CL429 increased mice survival, protected mice against the lethal damage of...

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Detalles Bibliográficos
Autores principales: Cheng, Ying, Du, Jicong, Liu, Ruling, Dong, Suhe, Cai, Jianming, Gao, Fu, Liu, Cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051721/
https://www.ncbi.nlm.nih.gov/pubmed/33609010
http://dx.doi.org/10.1111/jcmm.16252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051721/
https://www.ncbi.nlm.nih.gov/pubmed/33609010
http://dx.doi.org/10.1111/jcmm.16252

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