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Novel chimeric TLR2/NOD2 agonist CL429 exhibited significant radioprotective effects in mice
Severe ionizing radiation causes the acute lethal damage of haematopoietic system and gastrointestinal tract. Here, we found CL429, the novel chimeric TLR2/NOD2 agonist, exhibited significant radioprotective effects in mice. CL429 increased mice survival, protected mice against the lethal damage of...
Autores principales: | Cheng, Ying, Du, Jicong, Liu, Ruling, Dong, Suhe, Cai, Jianming, Gao, Fu, Liu, Cong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051721/ https://www.ncbi.nlm.nih.gov/pubmed/33609010 http://dx.doi.org/10.1111/jcmm.16252 |
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