Depressed β‐adrenergic inotropic responsiveness and intracellular calcium handling abnormalities in Duchenne Muscular Dystrophy patients’ induced pluripotent stem cell–derived cardiomyocytes

Duchenne muscular dystrophy (DMD), caused by mutations in the dystrophin gene, is an X‐linked disease affecting male and rarely adult heterozygous females, resulting in death by the late 20s to early 30s. Previous studies reported depressed left ventricular function in DMD patients which may result...

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Detalles Bibliográficos
Autores principales: Mekies, Lucy N., Regev, Danielle, Eisen, Binyamin, Fernandez‐Gracia, Jonatan, Baskin, Polina, Ben Jehuda, Ronen, Shulman, Rita, Reiter, Irina, Palty, Raz, Arad, Michael, Gottlieb, Eyal, Binah, Ofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051742/
https://www.ncbi.nlm.nih.gov/pubmed/33619882
http://dx.doi.org/10.1111/jcmm.16341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051742/
https://www.ncbi.nlm.nih.gov/pubmed/33619882
http://dx.doi.org/10.1111/jcmm.16341

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