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Interleukin-6: obstacles to targeting a complex cytokine in critical illness

Circulating concentrations of the pleiotropic cytokine interleukin-6 (IL-6) are known to be increased in pro-inflammatory critical care syndromes, such as sepsis and acute respiratory distress syndrome. Elevations in serum IL-6 concentrations in patients with severe COVID-19 have led to renewed inte...

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Detalles Bibliográficos
Autores principales: McElvaney, Oliver J, Curley, Gerard F, Rose-John, Stefan, McElvaney, Noel G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051931/
https://www.ncbi.nlm.nih.gov/pubmed/33872590
http://dx.doi.org/10.1016/S2213-2600(21)00103-X