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The LINC complex transmits integrin-dependent tension to the nuclear lamina and represses epidermal differentiation

While the mechanisms by which chemical signals control cell fate have been well studied, the impact of mechanical inputs on cell fate decisions is not well understood. Here, using the well-defined system of keratinocyte differentiation in the skin, we examine whether and how direct force transmissio...

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Detalles Bibliográficos
Autores principales: Carley, Emma, Stewart, Rachel M, Zieman, Abigail, Jalilian, Iman, King, Diane E, Zubek, Amanda, Lin, Samantha, Horsley, Valerie, King, Megan C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051949/
https://www.ncbi.nlm.nih.gov/pubmed/33779546
http://dx.doi.org/10.7554/eLife.58541