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Functional insights from a surface antigen mRNA-bound proteome

Trypanosoma brucei is the causative agent of human sleeping sickness. The parasites’ variant surface glycoprotein (VSG) enables them to evade adaptive immunity via antigenic variation. VSG comprises 10% of total cell protein and the high stability of VSG mRNA is essential for trypanosome survival. T...

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Detalles Bibliográficos
Autores principales: Melo do Nascimento, Larissa, Egler, Franziska, Arnold, Katharina, Papavasiliou, Nina, Clayton, Christine, Erben, Esteban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051951/
https://www.ncbi.nlm.nih.gov/pubmed/33783358
http://dx.doi.org/10.7554/eLife.68136