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Functional insights from a surface antigen mRNA-bound proteome
Trypanosoma brucei is the causative agent of human sleeping sickness. The parasites’ variant surface glycoprotein (VSG) enables them to evade adaptive immunity via antigenic variation. VSG comprises 10% of total cell protein and the high stability of VSG mRNA is essential for trypanosome survival. T...
Autores principales: | Melo do Nascimento, Larissa, Egler, Franziska, Arnold, Katharina, Papavasiliou, Nina, Clayton, Christine, Erben, Esteban |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051951/ https://www.ncbi.nlm.nih.gov/pubmed/33783358 http://dx.doi.org/10.7554/eLife.68136 |
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