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miR-375 Promotes Pancreatic Differentiation In Vitro by Affecting Different Target Genes at Different Stages

Human embryonic stem cells (hESCs) possess the ability to differentiate into insulin-producing cells (IPCs), which can be used to treat type I diabetes. miR-375 is an essential transcriptional regulator in the development and maturation of the pancreas. In this study, we optimized a protocol to diff...

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Detalles Bibliográficos
Autores principales: Lu, Zhenyu, Wang, Jing, Wang, Xu, Li, Zhiying, Niu, Dan, Wang, Min, Xiang, Jinzhu, Yue, Yongli, Xia, Yajuan, Li, Xueling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052179/
https://www.ncbi.nlm.nih.gov/pubmed/33897780
http://dx.doi.org/10.1155/2021/6642983