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Molecular features of tumor-derived genetic alterations in circulating cell-free DNA in virtue of autopsy analysis

In cancer patients, circulating cell-free DNA (cfDNA) includes tumor-derived DNA (tDNA). cfDNA has been used clinically for non-invasive gene mutation testing. The aim of this study was to characterize the features of the genetic alterations detected in cfDNA. This study included 6 patients with pri...

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Detalles Bibliográficos
Autores principales: Koba, Hayato, Kimura, Hideharu, Yoneda, Taro, Sone, Takashi, Ohkura, Noriyuki, Hara, Johsuke, Hosomichi, Kazuyoshi, Tajima, Atsushi, Kasahara, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052353/
https://www.ncbi.nlm.nih.gov/pubmed/33863951
http://dx.doi.org/10.1038/s41598-021-87094-1