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Interleukin-11-expressing fibroblasts have a unique gene signature correlated with poor prognosis of colorectal cancer

Interleukin (IL)-11 is a member of the IL-6 family of cytokines and is involved in multiple cellular responses, including tumor development. However, the origin and functions of IL-11-producing (IL-11(+)) cells are not fully understood. To characterize IL-11(+) cells in vivo, we generate Il11 report...

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Detalles Bibliográficos
Autores principales: Nishina, Takashi, Deguchi, Yutaka, Ohshima, Daisuke, Takeda, Wakami, Ohtsuka, Masato, Shichino, Shigeyuki, Ueha, Satoshi, Yamazaki, Soh, Kawauchi, Mika, Nakamura, Eri, Nishiyama, Chiharu, Kojima, Yuko, Adachi-Akahane, Satomi, Hasegawa, Mizuho, Nakayama, Mizuho, Oshima, Masanobu, Yagita, Hideo, Shibuya, Kazutoshi, Mikami, Tetuo, Inohara, Naohiro, Matsushima, Kouji, Tada, Norihiro, Nakano, Hiroyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052408/
https://www.ncbi.nlm.nih.gov/pubmed/33863879
http://dx.doi.org/10.1038/s41467-021-22450-3