Molecular analysis of cyclin D1 modulators PRKN and FBX4 as candidate tumor suppressors in sporadic parathyroid adenomas

OBJECTIVE: Primary hyperparathyroidism is most often caused by a sporadic single-gland parathyroid adenoma (PTA), a tumor type for which cyclin D1 is the only known and experimentally validated oncoprotein. However, the molecular origins of its frequent overexpression have remained mostly elusive. I...

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Detalles Bibliográficos
Autores principales: Brewer, Kelly, Nip, Isabel, Bellizzi, Justin, Costa-Guda, Jessica, Arnold, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052572/
https://www.ncbi.nlm.nih.gov/pubmed/33617468
http://dx.doi.org/10.1530/EC-21-0055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052572/
https://www.ncbi.nlm.nih.gov/pubmed/33617468
http://dx.doi.org/10.1530/EC-21-0055

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