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Silencing SHMT2 inhibits the progression of tongue squamous cell carcinoma through cell cycle regulation
BACKGROUND: Serine hydroxymethyltransferase 2 (SHMT2) is a vital metabolic enzyme in one carbon metabolism catalyzing the conversion of serine to glycine, which has been reported to play a crucial role in the progression of tumors. However, its function in tongue squamous cell carcinoma (TSCC) remai...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052717/ https://www.ncbi.nlm.nih.gov/pubmed/33863325 http://dx.doi.org/10.1186/s12935-021-01880-5 |