TriBAFF-CAR-T cells eliminate B-cell malignancies with BAFFR-expression and CD19 antigen loss

BACKGROUND: To investigate the effect of TriBAFF-CAR-T cells on hematological tumor cells. METHODS: TriBAFF-CAR-T and CD19-CAR-T cells were co-cultured with BAFFR-bearing B-cell malignancies at different effector/target ratios to evaluate the anti-tumor effects. In vivo, TriBAFF-CAR-T and CD19-CAR-T...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Guangchao, Zhang, Qing, Liu, Zhi, Shen, Huijuan, Zhu, Yangmin, Zhou, Zhao, Ding, Wen, Han, Siqi, Zhou, Jie, Ou, Ruiming, Luo, Min, Liu, Shuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052726/
https://www.ncbi.nlm.nih.gov/pubmed/33865370
http://dx.doi.org/10.1186/s12935-021-01923-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052726/
https://www.ncbi.nlm.nih.gov/pubmed/33865370
http://dx.doi.org/10.1186/s12935-021-01923-x

Ejemplares similares