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Glycol chitosan-based tacrolimus-loaded nanomicelle therapy ameliorates lupus nephritis

BACKGROUND: Recently, we developed hydrophobically modified glycol chitosan (HGC) nanomicelles loaded with tacrolimus (TAC) (HGC-TAC) for the targeted renal delivery of TAC. Herein, we determined whether the administration of the HGC-TAC nanomicelles decreases kidney injury in a model of lupus nephr...

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Detalles Bibliográficos
Autores principales: Kim, Chang Seong, Mathew, Ansuja Pulickal, Vasukutty, Arathy, Uthaman, Saji, Joo, Soo Yeon, Bae, Eun Hui, Ma, Seong Kwon, Park, In-Kyu, Kim, Soo Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052756/
https://www.ncbi.nlm.nih.gov/pubmed/33865397
http://dx.doi.org/10.1186/s12951-021-00857-w