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A novel all-in-one conditional knockout system uncovered an essential role of DDX1 in ribosomal RNA processing
Generation of conditional knockout (cKO) and various gene-modified cells is laborious and time-consuming. Here, we established an all-in-one cKO system, which enables highly efficient generation of cKO cells and simultaneous gene modifications, including epitope tagging and reporter gene knock-in. W...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053084/ https://www.ncbi.nlm.nih.gov/pubmed/33503245 http://dx.doi.org/10.1093/nar/gkaa1296 |