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Structural parameters of palindromic repeats determine the specificity of nuclease attack of secondary structures
Palindromic sequences are a potent source of chromosomal instability in many organisms and are implicated in the pathogenesis of human diseases. In this study, we investigate which nucleases are responsible for cleavage of the hairpin and cruciform structures and generation of double-strand breaks a...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053094/ https://www.ncbi.nlm.nih.gov/pubmed/33772579 http://dx.doi.org/10.1093/nar/gkab168 |