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A programmable pAgo nuclease with universal guide and target specificity from the mesophilic bacterium Kurthia massiliensis

Argonaute proteins are programmable nucleases that are found in both eukaryotes and prokaryotes and provide defense against invading genetic elements. Although some prokaryotic argonautes (pAgos) were shown to recognize RNA targets in vitro, the majority of studied pAgos have strict specificity towa...

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Detalles Bibliográficos
Autores principales: Kropocheva, Ekaterina, Kuzmenko, Anton, Aravin, Alexei A, Esyunina, Daria, Kulbachinskiy, Andrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053121/
https://www.ncbi.nlm.nih.gov/pubmed/33744962
http://dx.doi.org/10.1093/nar/gkab182