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A programmable pAgo nuclease with universal guide and target specificity from the mesophilic bacterium Kurthia massiliensis
Argonaute proteins are programmable nucleases that are found in both eukaryotes and prokaryotes and provide defense against invading genetic elements. Although some prokaryotic argonautes (pAgos) were shown to recognize RNA targets in vitro, the majority of studied pAgos have strict specificity towa...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053121/ https://www.ncbi.nlm.nih.gov/pubmed/33744962 http://dx.doi.org/10.1093/nar/gkab182 |