What defines a synthetic riboswitch? – Conformational dynamics of ciprofloxacin aptamers with similar binding affinities but varying regulatory potentials

Among the many in vitro-selected aptamers derived from SELEX protocols, only a small fraction has the potential to be applied for synthetic riboswitch engineering. Here, we present a comparative study of the binding properties of three different aptamers that bind to ciprofloxacin with similar K(D)...

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Detalles Bibliográficos
Autores principales: Kaiser, Christoph, Schneider, Jeannine, Groher, Florian, Suess, Beatrix, Wachtveitl, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053125/
https://www.ncbi.nlm.nih.gov/pubmed/33772594
http://dx.doi.org/10.1093/nar/gkab166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053125/
https://www.ncbi.nlm.nih.gov/pubmed/33772594
http://dx.doi.org/10.1093/nar/gkab166

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