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What defines a synthetic riboswitch? – Conformational dynamics of ciprofloxacin aptamers with similar binding affinities but varying regulatory potentials
Among the many in vitro-selected aptamers derived from SELEX protocols, only a small fraction has the potential to be applied for synthetic riboswitch engineering. Here, we present a comparative study of the binding properties of three different aptamers that bind to ciprofloxacin with similar K(D)...
Autores principales: | Kaiser, Christoph, Schneider, Jeannine, Groher, Florian, Suess, Beatrix, Wachtveitl, Josef |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053125/ https://www.ncbi.nlm.nih.gov/pubmed/33772594 http://dx.doi.org/10.1093/nar/gkab166 |
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