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Androgen and glucocorticoid receptor direct distinct transcriptional programs by receptor-specific and shared DNA binding sites

The glucocorticoid (GR) and androgen (AR) receptors execute unique functions in vivo, yet have nearly identical DNA binding specificities. To identify mechanisms that facilitate functional diversification among these transcription factor paralogs, we studied them in an equivalent cellular context. A...

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Detalles Bibliográficos
Autores principales: Kulik, Marina, Bothe, Melissa, Kibar, Gözde, Fuchs, Alisa, Schöne, Stefanie, Prekovic, Stefan, Mayayo-Peralta, Isabel, Chung, Ho-Ryun, Zwart, Wilbert, Helsen, Christine, Claessens, Frank, Meijsing, Sebastiaan H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053126/
https://www.ncbi.nlm.nih.gov/pubmed/33751115
http://dx.doi.org/10.1093/nar/gkab185