Structures of Neisseria gonorrhoeae MtrR-operator complexes reveal molecular mechanisms of DNA recognition and antibiotic resistance-conferring clinical mutations

Mutations within the mtrR gene are commonly found amongst multidrug resistant clinical isolates of Neisseria gonorrhoeae, which has been labelled a superbug by the Centers for Disease Control and Prevention. These mutations appear to contribute to antibiotic resistance by interfering with the abilit...

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Detalles Bibliográficos
Autores principales: Beggs, Grace A, Ayala, Julio C, Kavanaugh, Logan G, Read, Timothy D, Hooks, Grace M, Schumacher, Maria A, Shafer, William M, Brennan, Richard G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053128/
https://www.ncbi.nlm.nih.gov/pubmed/33784401
http://dx.doi.org/10.1093/nar/gkab213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053128/
https://www.ncbi.nlm.nih.gov/pubmed/33784401
http://dx.doi.org/10.1093/nar/gkab213

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