Network controllability-based algorithm to target personalized driver genes for discovering combinatorial drugs of individual patients

Multiple driver genes in individual patient samples may cause resistance to individual drugs in precision medicine. However, current computational methods have not studied how to fill the gap between personalized driver gene identification and combinatorial drug discovery for individual patients. He...

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Detalles Bibliográficos
Autores principales: Guo, Wei-Feng, Zhang, Shao-Wu, Feng, Yue-Hua, Liang, Jing, Zeng, Tao, Chen, Luonan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053130/
https://www.ncbi.nlm.nih.gov/pubmed/33434272
http://dx.doi.org/10.1093/nar/gkaa1272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053130/
https://www.ncbi.nlm.nih.gov/pubmed/33434272
http://dx.doi.org/10.1093/nar/gkaa1272

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