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Network controllability-based algorithm to target personalized driver genes for discovering combinatorial drugs of individual patients
Multiple driver genes in individual patient samples may cause resistance to individual drugs in precision medicine. However, current computational methods have not studied how to fill the gap between personalized driver gene identification and combinatorial drug discovery for individual patients. He...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053130/ https://www.ncbi.nlm.nih.gov/pubmed/33434272 http://dx.doi.org/10.1093/nar/gkaa1272 |