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Sequence-dependent cost for Z-form shapes the torsion-driven B–Z transition via close interplay of Z-DNA and DNA bubble

Despite recent genome-wide investigations of functional DNA elements, the mechanistic details about their actions remain elusive. One intriguing possibility is that DNA sequences with special patterns play biological roles, adopting non-B-DNA conformations. Here we investigated dynamics of thymine-g...

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Detalles Bibliográficos
Autores principales: Kim, Sook Ho, Jung, Hae Jun, Lee, Il-Buem, Lee, Nam-Kyung, Hong, Seok-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053131/
https://www.ncbi.nlm.nih.gov/pubmed/33744929
http://dx.doi.org/10.1093/nar/gkab153