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Upregulation of Fecal Epithelial Heparanase mRNA Is Associated with Increased Ulcerative Colitis Activity and Cancerization Risk

BACKGROUND: Heparanase (HPSE) is considered to play an important role in the occurrence, development and carcinogenesis of ulcerative colitis (UC). There are no reports about the detection of HPSE mRNA in feces to predict UC activity and cancerization risk. AIMS: To explore the feasibility and effec...

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Detalles Bibliográficos
Autores principales: Cui, Ying, Zhang, Jun, Chen, Yan, Chen, Le-gao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053146/
https://www.ncbi.nlm.nih.gov/pubmed/32445051
http://dx.doi.org/10.1007/s10620-020-06350-y