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Combination of novel intravesical xenogeneic urothelial cell immunotherapy and chemotherapy enhances anti-tumor efficacy in preclinical murine bladder tumor models

BACKGROUND: Immune checkpoint inhibitors induce robust and durable responses in advanced bladder cancer (BC), but only for a subset of patients. Xenovaccination has been proposed as an effective immunotherapeutic approach to induce anti-tumor immunity. Thus, we proposed a novel intravesical xenogene...

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Detalles Bibliográficos
Autores principales: Huang, Chi-Ping, Wu, Chun-Chie, Shyr, Chih-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053151/
https://www.ncbi.nlm.nih.gov/pubmed/33156394
http://dx.doi.org/10.1007/s00262-020-02775-6