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Precision modeling of gall bladder cancer patients in mice based on orthotopic implantation of organoid-derived tumor buds
Genetically engineered mice (GEM) are the gold standard for cancer modeling. However, strict recapitulation of stepwise carcinogenesis from a single tumor-initiating epithelial cell among genetically intact cells in adults is not feasible with the currently available techniques using GEM. In previou...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053198/ https://www.ncbi.nlm.nih.gov/pubmed/33866327 http://dx.doi.org/10.1038/s41389-021-00322-1 |