Precision modeling of gall bladder cancer patients in mice based on orthotopic implantation of organoid-derived tumor buds

Genetically engineered mice (GEM) are the gold standard for cancer modeling. However, strict recapitulation of stepwise carcinogenesis from a single tumor-initiating epithelial cell among genetically intact cells in adults is not feasible with the currently available techniques using GEM. In previou...

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Detalles Bibliográficos
Autores principales: Kato, Shingo, Fushimi, Kentaro, Yabuki, Yuichiro, Maru, Yoshiaki, Hasegawa, Sho, Matsuura, Tetsuya, Kurotaki, Daisuke, Suzuki, Akihiro, Kobayashi, Noritoshi, Yoneda, Masato, Higurashi, Takuma, Enaka, Makiko, Tamura, Tomohiko, Hippo, Yoshitaka, Nakajima, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053198/
https://www.ncbi.nlm.nih.gov/pubmed/33866327
http://dx.doi.org/10.1038/s41389-021-00322-1

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