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Mendelian randomization integrating GWAS and eQTL data revealed genes pleiotropically associated with major depressive disorder

Previous genome-wide association studies (GWAS) have identified potential genetic variants associated with the risk of major depressive disorder (MDD), but the underlying biological interpretation remains largely unknown. We aimed to prioritize genes that were pleiotropically or potentially causally...

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Detalles Bibliográficos
Autores principales: Yang, Huarong, Liu, Di, Zhao, Chuntao, Feng, Bowen, Lu, Wenjin, Yang, Xiaohan, Xu, Minglu, Zhou, Weizhu, Jing, Huiquan, Yang, Jingyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053199/
https://www.ncbi.nlm.nih.gov/pubmed/33866329
http://dx.doi.org/10.1038/s41398-021-01348-0