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Vitamin K antagonist anticoagulant usage is associated with increased incidence and progression of osteoarthritis
OBJECTIVES: Vitamin K is hypothesised to play a role in osteoarthritis (OA) pathogenesis through effects on vitamin K-dependent bone and cartilage proteins, and therefore may represent a modifiable risk factor. A genetic variant in a vitamin K-dependent protein that is an essential inhibitor for car...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053344/ https://www.ncbi.nlm.nih.gov/pubmed/34412027 http://dx.doi.org/10.1136/annrheumdis-2020-219483 |