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Vitamin K antagonist anticoagulant usage is associated with increased incidence and progression of osteoarthritis

OBJECTIVES: Vitamin K is hypothesised to play a role in osteoarthritis (OA) pathogenesis through effects on vitamin K-dependent bone and cartilage proteins, and therefore may represent a modifiable risk factor. A genetic variant in a vitamin K-dependent protein that is an essential inhibitor for car...

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Detalles Bibliográficos
Autores principales:	Boer, Cindy G, Szilagyi, Ingrid, Nguyen, N Long, Neogi, Tuhina, Meulenbelt, Ingrid, Ikram, M Arfan, Uitterlinden, André G, Bierma-Zeinstra, Sita, Stricker, Bruno H, van Meurs, Joyce B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Osteoarthritis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053344/ https://www.ncbi.nlm.nih.gov/pubmed/34412027 http://dx.doi.org/10.1136/annrheumdis-2020-219483

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