Label-Free Screening of SARS-CoV-2 NSP14 Exonuclease Activity Using SAMDI Mass Spectrometry

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus responsible for the global COVID-19 pandemic. Nonstructural protein 14 (NSP14), which features exonuclease (ExoN) and guanine N7 methyltransferase activity, is a critical player in SARS-CoV-2 replication and fidelity and repre...

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Detalles Bibliográficos
Autores principales: Scholle, Michael D., Liu, Cheng, Deval, Jerome, Gurard-Levin, Zachary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Laboratory Automation and Screening. Published by Elsevier Inc. 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053483/
https://www.ncbi.nlm.nih.gov/pubmed/33870746
http://dx.doi.org/10.1177/24725552211008854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053483/
https://www.ncbi.nlm.nih.gov/pubmed/33870746
http://dx.doi.org/10.1177/24725552211008854

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