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Age-dependency of terminal ileum tissue resident memory T cell responsiveness profiles to S. Typhi following oral Ty21a immunization in humans

BACKGROUND: The impact of aging on the immune system is unequivocal and results in an altered immune status termed immunosenescence. In humans, the mechanisms of immunosenescence have been examined almost exclusively in blood. However, most immune cells are present in tissue compartments and exhibit...

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Detalles Bibliográficos
Autores principales: Booth, Jayaum S., Goldberg, Eric, Patil, Seema A., Barnes, Robin S., Greenwald, Bruce D., Sztein, Marcelo B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053564/
https://www.ncbi.nlm.nih.gov/pubmed/33874975
http://dx.doi.org/10.1186/s12979-021-00227-y